In Genetic Entropy, Dr. John Sanford, former Cornell University professor of genetics and inventor of the "gene gun" process, takes up the challenge to, well, challenge, the theory of evolution by undermining its most "sacred cow": natural selection and mutations. No, Dr. Sanford does not deny the reality of these two processes, but he questions the idea that they can bring about the kind of change required by goo-to-you-via-the-zoo evolution. The results of his study are devastating to a naturalistic view of origins.
Simply put, mutations are almost always "nearly-neutral", meaning that they don't have much of an effect on an organism at large (which is what selection really "selects" for). Only when these mutations add up do they really cause problems. Why is this a problem for evolution? Well, if mutations don't have much of an effect on an organism by themselves (except the for the really bad ones considered "lethal") how can natural selection do its selecting work, picking out the best and weeding out the worst? It can't! Worse yet, natural selection can't even keep our genetic code from breaking down! You see, the hundreds of genetic mistakes we inherit and acquire each generation are adding up to one genetic disaster. If selection were to weed out these mistakes by preventing individuals with a certain mistake from reproducing, it would have to ignore all the other hundreds of mistakes, but if it were to select against a number of mistakes in a population, it would not be able to do much selecting, because the population would decrease and eventually go extinct. Beyond these problems, natural selection is often interfered with by non-genetic factors such as disease, environment, epigenetics ("above genetics"), chance, probability, and gametic sampling.
Because of natural selection's inability to prevent the genome from breaking down, genetic entropy is certain. In other words, nothing can keep our genetic code from breaking down. If this is the case, how can evolutionists say that the genome is improving and gaining information? The answer: they can't (consistently). This downward curve toward genetic destruction fits the biblical model of perfect creation, the Fall, and the Curse, but not evolution.
This book is a reality check for evolution, providing believers with a powerful tool to refute evolutionary speculation and the potential to force many in modern academia to rethink their most unquestioned theories. I highly recommend this well-researched book!
Thanks for reading!
~ Caleb LePore